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Ketoacidosis
Posted: 04.01.2009
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Ketoacidosis

What are Ketones?

In diabetes, there is not enough insulin to help your muscles absorb glucose from the blood. And when your muscles are starved for energy they start to "burn" fat. This produces breakdown products called ketones. These are toxic acids. The accumulation of these acids in the body may lead to the condition called ketosis and as it gets more serious, ketoacidosis or DKA.

Diabetic Ketoacidosis (DKA)

  • Occurs when excessive levels of ketone accumulate and the body becomes acidotic.
  • It is a potentially life-threatening condition.
  • ß-Hydroxybutyrate is the predominant ketone associated with DKA.

ß-Hydroxybutyrate: A key to DKA Detection, Better Clinical Decisions

Sick-day management requires increased monitoring of blood glucose and assessment for ketosis. Testing for ß-Hydroxybutyrate is a key to early diabetic ketoacidosis (DKA) detection. Blood ketone testing methods are now available for monitoring ketoacidosis.

Clinically Accurate ß-Hydroxybutyrate Measurements
ß-Hydroxybutyrate Reading Interpretation
1.6 to 3.0 mmol/L Readings above 1.5 indicate you may be at risk of developing diabetic ketoacidosis or DKA. Contact your healthcare provider immediately for advice
0.6 to 1.5 mmol/L Readings between 0.6 and 1.5 may indicate the development of a problem that may require medical assistance. Follow your healthcare provider's instructions.
Below 0.6 mmol/L Readings below 0.6 are in the normal range.

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Important Notice: Information provided is for general background purposes and is not intended as a substitute for medical diagnosis or treatment by a trained professional. You should always consult your physician about any health care questions you may have, especially before trying a new medication, diet, fitness program, or approach to health care issues.

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